Crossover studies in medicine and public health
https://doi.org/10.22328/2413-5747-2024-10-2-45-57
Abstract
In this paper we present an overview of the design of crossover study, as well as its special variant, the case-crossover study, which refers to hybrid studies. The methodological features of these research designs are outlined. Main research questions that can be addressed using these study designs and the possibilities of interpreting the information received are presented. Strengths and limitations of these study designs will be described in detail. Examples of cross-sectional studies in the medical literature are presented and analyzed.
About the Authors
Kamila K. Kholmatova
Northern State Medical University
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Associate professor at the Department of Internal Medicine and Endocrinology
Maria A. Gorbatova
Northern State Medical University
Russian Federation
Russian Federation
Cand. of Sci. (Med.), MPH, Associate professor at the Department of Pediatric Dentistry
Olga A. Kharkova
Northern State Medical University
Russian Federation
Russian Federation
Cand. of Sci. (Med.), Associate professor at the Department of Pedagogics and Psychology
Andrej M. Grjibovski
Northern State Medical University
Russian Federation
Russian Federation
Dr of Sci. (Med.), Master of International Community Health, Head of the Directorate for Research and Innovations
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1. Fig. 1. Crossover study design | |
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2. Fig. 2. Case-crossover design. | |
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3. Fig. 3. Study design for bioequivalence assessment of Glucophage® manufactured in China and in France | |
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For citations:
Kholmatova K.K., Gorbatova M.A., Kharkova O.A., Grjibovski A.M. Crossover studies in medicine and public health. Marine Medicine. 2024;10(2):45-57. (In Russ.) https://doi.org/10.22328/2413-5747-2024-10-2-45-57
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