PHYSIOLOGICAL SUBSTANTIATION OF DETERMINING THE RESISTANCE OF DIVERS TO THE TOXIC EFFECT OF OXYGEN USING ORAL STRESS RENAL TESTS
https://doi.org/10.22328/2413-5747-2020-6-3-50-59
Abstract
Aim of the work: to identify changes in renal function under the action of dosed hyperoxia using oral stress renal tests and to determine the relationship between the state of the functions of the excretory system and the body’s resistance to toxic effects of oxygen.
Materials and methods. A survey of 44 men was carried out. Changes in water-electrolyte metabolism and renal function were determined using developed oral renal stress tests.
Results and discussion. It has been shown that the normal functioning of the excretory system plays an important role in the high human resistance to the toxic effects of oxygen.
About the Authors
D. P. ZverevRussian Federation
A. A. Myasnikov
Russian Federation
A. Yu. Shitov
Russian Federation
V. I. Chernov
Russian Federation
A. N. Andrusenko
Russian Federation
I. R. Klenkov
Russian Federation
Z. M. Israfilov
Russian Federation
References
1. Yakhontov B.O. Physiological aspects provisions the life activity of the divers in increased pressure in the hyperbaric chamber. International Journal of Applied and Basic Research, 2018, No. 6, pp. 135–139 (In Russ.).
2. Novikov M.V., Svistov A.S., Chumakov A.V., Makiev R.G., Shahnovich P.G., Kutelev G.G., Efimov S.V. About influence of some potentially dangerous hyperbaric factors on microcirculation of navy divers. Herald of the Russian Academy of Military Medicine, 2015, No. 3 (51), pp. 41–44 (In Russ.).
3. Levchenko Z.A., Nazarov S.S., Yatmanov A.N. Physiological and psychological features of divers with different levels of resistance to decompression disease. Proceedings of the Russian Academy of Military Medicine, 2019, Vol. 38, No 3, pp. 197–201 (In Russ.).
4. Alpatov V. N., Yatmanov A.N. Predictors of resistance to decompression gas formation at professional divers. Extreme Human Activity, 2019, No. 2 (52), pp. 3–6 (In Russ.).
5. Vyotosh A.N,, Alekseeva O.S. Stopping the toxic effect of hyperbaric oxygen by adding nitrous oxide to the respiratory gas environment. Hyperbaric physiology and medicine, 2018, No. 1, pp. 25–29 (In Russ.).
6. Makarov A.F., Kotskiy M.A., Buhtiyarov I.V. Аrtificial hypobiosis as a method reducing negative effects of oxygen when at increased partial pressure (oxygen intoxication). Occupational medicine and industrial ecology, 2017, No. 9, р. 116 (In Russ.).
7. Statsenko A.V. The prognostic tests of organism stability to toxic oxygen exposure. Herald of the Russian Academy of Military Medicine, 2008, No. 2 (22), pp. 104–107 (In Russ.).
8. Sementsov V.N., Ivanov I.V. Functional tests for professional screening of divers and caissons. Proceedings of the Russian Academy of Military Medicine, 2019, Vol. 38, No 3, pp. 207–216 (In Russ.).
9. Sementsov V.N., Ivanov I.V. Functional tests as an important direction of divers’ health preservation. Medicina truda ipromyshlennaya ekologiya, 2019, Vol. 59, No. 9, р. 745 (In Russ.). doi: 10.31089/1026-9428-2019-59-9-745-746.
10. Konovalov V.S. Safety criteria for diving operations with compressed oxygen. Herald of the Russian Academy of Military Medicine, 2008, No. 2 (22), pp. 89–92 (In Russ.).
11. Zverev D.P., Myasnikov A.A., Shitov A.Yu., Andrusenko A.N., Chernov V.I., Klenkov I.R. The use of oral stress renal tests to determine the resistance of divers to hyperbaric factors. Military Medical Journal, 2020, Vol. 341, No. 2, pp. 66–72 (In Russ.).
12. Molchanov D.V. Kidneys with hyperoxia. Moscow, Publishing house BINOM, 2015, 160 p. ISBN 978–5-9518–0640–6 (In Russ.).
13. Grigoriev A. I., Nikolaev S.O., Orlov O.I., SeТом 6 № 3/2020 г. Морская медицина 57 menov V.Yu., Perfileva T.A. The effect of hyperbaria on water-salt metabolism. Space Biology and Medicine, 1985, No. 2–3, pp. 3–44 (In Russ.).
14. Shitov A.Yu. Decompression sickness: prophylaxis in divers taking into account the mechanisms of regulation of water-electrolyte metabolism. Saarbrucken, Germany, LAP LAMBERT Academic Publishing GmbH & Co. KG, 2011. 259 р. ISBN 978-3-8465-0088-0 (In Russ.).
15. Grigoriev A.I., Larina I. M., Noskov V. B. The influence of space flights on water-electrolytes turnover and its regulation. Russian Physiological Journal, 2006, Vol. 92, No. 1, pp. 5–17 (In Russ.).
16. Gozhenko A. I., Kuksan N. I., Gozhenko E. A. Method of definition in renal functional reserve in healthy individuals. Nephrology, 2001, Vol. 5, No. 4, pp. 70–73 (In Russ.).
17. Lebedeva T.L. The state of homeostatic functions of kidneys at water-salt loads. Actual problems of transport medicine, 2011, No. 2 (24), pp. 93–96 (In Russ.).
18. Medvedev L.G., Statsenko A.V., Apchel V.Ya., Baklanov D.V., Dmitryk A.I., Lupanov A.I. The mechanism of disorders of the brain in oxygen poisoning and nitrogen narcosis in divers and submariners. Herald of the Russian Academy of Military Medicine, 2012, No. 2 (38), pp. 74–78 (In Russ.).
19. Finkinshtein Ya.D., Aisman R.I., Terner А.Ya., Pantyukhin I.V. The reflex mechanism of the potassium homeostasis regulation. Physiological journal of the USSR, 1973, Vol. 59, No. 9, pp. 1429–1436 (In Russ.).
20. Detyen P. Kidney Function. Human Physiology, еd. R. Schmidt, G. Teus. trans. from English. Moscow, Рublishing house Mir, 2010, pp. 785–812 (In Russ.).
21. Gozhenko A.I., Dolomatov S.I., Shumilova P.A., Topor E.A., Pyatenko V.A., Badiin I.Yu. Effects of osmotic loads on the functional state of the kidneys in healthy volunteers. Nephrology, 2004, Vol. 8, No. 2, pp. 44–48 (In Russ.).
22. Ondar A.O., Melnikov V.N., Krivoschekov S.G., Aizman R.I. Changes in peripheral hemodynamics under water load for healthy men. VI Siberian Physiological Congress (Barnaul, 25–27 June 2008), Barnaul. Printexpress, 2008, pp. 138–139 (In Russ.).
23. Morukov B.V., Grigoryev A.I. The response of a healthy person to the administration of calcium lactate. Human Physiology, 1978, Vol. 4, No. 5, pp. 894–898. (In Russ.).
24. Grigoriev A.I., Noskov V.B. Functional test with potassium chloride following long-term space missions. Aerospace and Environmental Medicine (Russia), 1997, Vol. 31, No. 5, pp. 15–19 (In Russ.).
25. Marina A.S., Kutina A.V. Ion-regulating kidney function under conditions of preoral and parenteral potassium loads. Sechenov physiological journal of the Russia, 2013, Vol. 99, No. 3, pp. 372–382 (In Russ.).
26. Aizman R. I., Finkinshtein Ya. D. On the liver osmo- and ionic receptors. Sechenov physiological journal of the USSR, 1976, Vol. 62, No. 1, pp. 128–136 (In Russ.). Marine medicine Vol. 6 No. 3/2020 58
27. Aizman R.I. The effect of water-potassium stress test on kidney function. Human Physiology, 1981, Vol. 7, No. 4, pp. 687–692 (In Russ.).
28. Aizman R.I., Golovin M.S., Girenko L.A. Age-specific features in renal response to food intakes and training loads in young professional skiers. Human Physiology, 2014, Vol. 40, No. 4, pp. 110–115 (In Russ.). doi: 10.7868/S013116461404002X.
Review
For citations:
Zverev D.P., Myasnikov A.A., Shitov A.Yu., Chernov V.I., Andrusenko A.N., Klenkov I.R., Israfilov Z.M. PHYSIOLOGICAL SUBSTANTIATION OF DETERMINING THE RESISTANCE OF DIVERS TO THE TOXIC EFFECT OF OXYGEN USING ORAL STRESS RENAL TESTS. Marine Medicine. 2020;6(3):50-59. (In Russ.) https://doi.org/10.22328/2413-5747-2020-6-3-50-59