CURRENT CONCEPTS OF THE PATHOGENESIS, PREVENTION AND TREATMENT OF THE MOTION DISEASE (SEASICKNESS)
https://doi.org/10.22328/2413-5747-2017-3-2-25-33
Abstract
Motion disease (naupathia, seasickness) is quite prevalent among otherwise healthy people and is manifested as travel sickness associated with nausea. It is a complex physiological response to certain motor stimuli caused by ship rocking, aircraft swinging or zero gravity. The motor stimuli may be both real (ship rocking) and virtual (watching a 3D movie). During the last decade, numerous studies addressed different stimuli that can cause naupathia, and numerous hypotheses have been put forward to explain it (sensory conflict, postural instability etc.) from the point of view of neural plasticity. However, no consensus concerning the origin of the specific clinical pattern of naupathia (nausea, vomiting, drowsiness, dysphoria etc.) has emerged by now. Several drugs and behavioral recommendations have been suggested for prevention and treatment of naupathia. Further studies of this condition using such techniques as videonystagmography and computer-assisted posturegraphy, as well as genetic analysis, are warranted.
About the Authors
I. V. Litvinenko
S. M. Kirov Military Medical Academy
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
I. N. Samartsev
S. M. Kirov Military Medical Academy
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
S. A. Zhivolupov
S. M. Kirov Military Medical Academy
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
M. V. Morozova
S. M. Kirov Military Medical Academy
Russian Federation
St. Petersburg
Russian Federation
St. Petersburg
References
1. Wang J., Lewis R.F. Contribution of intravestibular sensory conflict to motion sickness and dizziness in migraine disorders, J. Neurophysiol., 2016, Vol. 116 (4), рр. 1586–1591.
2. Bertolini G., Straumann D. Moving in a Moving World: A Review on Vestibular Motion Sickness. Front. Neurol., 2016, Vol. 15, рр. 7–14.
3. Sokolova T.P. Formirovanie vestibulyarnoj ustojchivosti sredstvami fizicheskoj kul’tury: metodicheskie ukazaniya dlya kursantov i studentov tekhnicheskih special’nostej ochnoj formy obucheniya. Petropavlovsk-Kamchatskij: KamchatGTU, 2008, 19 р. (In Russ.).
4. Reason J.T. Motion sickness adaptation: a neural mismatch model. J. R. Soc. Med., 1978, Vol. 71 (11), рр. 819–829.
5. Paillard A.C. et al. Motion sickness susceptibility in healthy subjects and vestibular patients: effects of gender, age and trait-anxiety. J. Vestib. Res., 2013, Vol. 23 (4–5), рр. 203–209.
6. Zhivolupov C.A., Samarcev I.N., Syroezhkin F.A. Sovremennaya koncepciya nejroplastichnosti, Zhurnal nevrologii i psihiatrii im. S.S. Korsakova, 2013, No. 10, рр. 102–108. (In Russ.).
7. Treisman M. Motion sickness, an evolutionary hypothesis. Science, 1977, Vol. 197, рр. 493–495.
8. Morrow G.R. The effect of a susceptibility to motion sickness on the side effects of cancer chemotherapy. Cancer, 1985, Vol. 55, рр. 2766–2770.
9. Money K.E., Cheung B.S. Another function of the inner ear, facilitation of the emetic response to poisons. Aviat. Space Environ. Med., 1983, Vol. 54, рр. 208–211.
10. Stoffregen T.A., Riccio G.E. An ecological theory of orientation and the vestibular system. Psychol. Rev., 1988, Vol. 95 (1), рр. 3–14.
11. Nathan A. OTC advice on travel sickness. The Phanrraceuticnl Journal, 2006, Vol. 276, рр. 395–398.
12. Gupta V.K. Motion sickness is linked to nystagmus-related trigeminal brain stem input: a new hypothesis. Med. Hypotheses., 2005, Vol. 64 (6), рр. 1177–1181.
13. Zhivolupov C.A., Samarcev I.N. Golovokruzhenie v nevrologii. Moscow, 2014, 208 р. (In Russ.).
14. Odinak M.M., Shcherbuk Yu.A., Shuleshova N.V., Bersnev V.P., Litvinenko I.V. Spravochnik vracha-nevrologa. Moscow, 2008, 575 р. (In Russ.).
15. Solov’ev A.V. Prognozirovanie ustojchivosti cheloveka k ukachivaniyu na osnove psihofiziologicheskih i konstitucional’no-tipologicheskih osobennosti: avtoref. dis. na soisk. uchen. st. d-ra med. nauk. Saint-Petersburg, 1997, 40 р. (In Russ.).
16. Buhtiyarov I.V. Vorob’ev O.A., Homenko M.N. Vzaimodejstvie zritel’noj, vestibulyarnoj i proprioceptivnoj sistem v processe prostranstvennoj orientirovki cheloveka v usloviya vozdejstviya bokovyh i prodol’nobokovyh peregruzok. Aviakosmicheskaya i ehkologicheskaya medicina, 2002, Vol. 36, No. 6, рр. 3–8 (In Russ.).
17. Holtmann S., Clarke A.H., Scherer H., Höhn M. The anti-motion sickness mechanism of ginger. A comparative study with placebo and dimenhydrinate. Acta Otolaryngol., 1989, Vol. 108 (3–4), рр. 168–174.
18. Muth E.R., Jokerst M., Stern R.M., Koch K.L. Effects of dimenhydrinate on gastric tachyarrhythmia and symptoms of vection-induced motion sickness. Aviat. Space Environ. Med., 1995, Vol. 66 (11), рр. 1041–1045.
19. Pyykkö I. et al. The effects of TTS-scopolamine, dimenhydrinate, lidocaine, and tocainide on motion sickness, vertigo, and nystagmus. Aviat. Space Environ. Med., 1985, Vol. 56 (8), рр. 777–782.
20. McClure J.A., Lycett P., Baskerville J.C. Diazepam as an antimotion sickness drug. J. Otolaryngol., 1982, Vol. 11 (4), рр. 253–259.
21. Muth E.R., Elkins A.N. High dose ondansetron for reduсting motion sickness in highly susceptible subjects. Aviat. Space Environ. Med., 2007, Vol. 78 (7), рр. 686–692.
22. Grøntved A., Brask T., Kambskard J., Hentzer E. Ginger root against seasickness. A controlled trial on the open sea. Acta Otolaryngol., 1988, Vol. 105 (1–2), рр. 45–49.
23. Horing B. et al. Reduction of motion sickness with an enhanced placebo instruction: an experimental study with healthy participants. Psychosom Med., 2013, Vol. 75 (5), рр. 497–504.
Review
For citations:
Litvinenko I.V., Samartsev I.N., Zhivolupov S.A., Morozova M.V. CURRENT CONCEPTS OF THE PATHOGENESIS, PREVENTION AND TREATMENT OF THE MOTION DISEASE (SEASICKNESS). Marine Medicine. 2017;3(2):25-33. (In Russ.) https://doi.org/10.22328/2413-5747-2017-3-2-25-33
Views:
3
Email this article 
