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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">seamed</journal-id><journal-title-group><journal-title xml:lang="ru">Морская медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Marine Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2413-5747</issn><issn pub-type="epub">2587-7828</issn><publisher><publisher-name>Research Institute of Industrial and Maritime Medicine of the Federal Medical and Biological Agency</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22328/2413-5747-2023-9-2-68-76</article-id><article-id custom-type="edn" pub-id-type="custom">MYQLYD</article-id><article-id custom-type="elpub" pub-id-type="custom">seamed-655</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИННОВАЦИОННЫЕ РАЗРАБОТКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INNOVATIVE DEVELOPMENTS</subject></subj-group></article-categories><title-group><article-title>Ретроспективный анализ профиля жирных кислот крови сотрудников силовых ведомств</article-title><trans-title-group xml:lang="en"><trans-title>Retrospective analysis of blood fatty acids profile on member of the military</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4849-4735</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Людинина</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyudinina</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Людинина Александра Юрьевна — кандидат  биологических наук, старший научный сотрудник  отдела экологической и медицинской физиологии</p><p>167982, г. Сыктывкар, ул. Первомайская, д. 50;</p><p>старший преподаватель кафедры биохимии и физиологии</p><p>г. Сыктывкар</p></bio><bio xml:lang="en"><p>Alexandra Yu. Lyudinina — Cand. of Sci. (Biol.), Senior Researcher Department of Ecological and Medical Physiology</p><p>167982, Syktyvkar, Pervomayskaya str., 50;</p><p>Senior Lecturer of the Biochemistry and Physiology Department</p><p>Syktyvkar</p></bio><email xlink:type="simple">salu_06@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1862-6936</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паршукова</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Parshukova</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Паршукова Ольга Ивановна — кандидат  биологических наук, научный сотрудник отдела экологической и медицинской физиологии</p><p>167982, г. Сыктывкар, ул. Первомайская, д. 50;</p><p>доцент кафедры биохимии и физиологии</p><p>г. Сыктывкар</p></bio><bio xml:lang="en"><p>Olga I. Parshukova — Cand. of Sci. (Biol.), Researcher  Department of Ecological and Medical Physiology</p><p>167982, Syktyvkar, Pervomayskaya str., 50;</p><p>Lecturer of the Biochemistry and Physiology Department</p><p>Syktyvkar</p></bio><email xlink:type="simple">olga-parshukova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8027-898X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бойко</surname><given-names>Е. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Bojko</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бойко Евгений Рафаилович — доктор медицинских  наук, профессор, директор</p><p>167982, г. Сыктывкар, ул. Первомайская, д. 50;</p><p>заведующий кафедры биохимии и физиологии</p><p>г. Сыктывкар</p></bio><bio xml:lang="en"><p>Evgeny R. Bojko  — Dr. of Sci. (Med.), Professor, Director Department of Ecological and Medical Physiology</p><p>167982, Syktyvkar, Pervomayskaya str., 50;</p><p>Head of the Biochemistry and Physiology Department</p><p>Syktyvkar</p></bio><email xlink:type="simple">boiko60@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт физиологии Федерального исследовательского центра Коми научного центра УрО РАН;&#13;
Сыктывкарский государственный университет им. П. Сорокина</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Physiology, Ural Branch, Russian Academy of Sciences;&#13;
Pitirim Sorokin Syktyvkar State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>20</day><month>07</month><year>2023</year></pub-date><volume>9</volume><issue>2</issue><fpage>68</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Людинина А.Ю., Паршукова О.И., Бойко Е.Р., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Людинина А.Ю., Паршукова О.И., Бойко Е.Р.</copyright-holder><copyright-holder xml:lang="en">Lyudinina A.Y., Parshukova O.I., Bojko E.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://seamed.elpub.ru/jour/article/view/655">https://seamed.elpub.ru/jour/article/view/655</self-uri><abstract><p>ВВЕДЕНИЕ: Изучение профиля жирных кислот (ЖК) как энергетического и функционального звена физической работоспособности у представителей силовых структур на разных этапах несения службы представляется весьма актуальным.ЦЕЛЬ: Оценить влияние боевого стресса на профиль ЖК крови сотрудников силовых структур.МАТЕРИАЛЫ И МЕТОДЫ: Ретроспективно проведен анализ профиля ЖК плазмы крови у 25 сотрудников отряда специального назначения ОМОНа до и после 4-месячной служебной командировки по выполнению специального задания, связанного с риском для здоровья и жизни. Группа сравнения (n = 12) – военнослужащие МЧС. Уровень пула ЖК в общих липидах плазмы крови определяли методом газовой хроматографии.РЕЗУЛЬТАТЫ: При первичном обследовании сотрудников спецназа выявлена более высокая доля гиперхолестеринемичной миристиновой кислоты в обеих группах относительно рекомендуемой нормы. Уровень этой кислоты у сотрудников ОМОНа составлял в среднем 1,5 mol % и был значимо выше, чем у мужчин группы сравнения (p = 0,028). Установлен сниженный относительно фоновых значений уровень эссенциальных n-3 полиненасыщенных жирных кислот (ПНЖК) в плазме крови (α-линоленовой и эйкозапентаеновой) у сотрудников ОМОНа на фоне высокой доли n-6 линолевой кислоты, о чем свидетельствует высокое значение индекса n-6/n-3 – 13.8/1 (при рекомендуемых нормах ВОЗ 5–7/1). Повторное обследование сотрудников ОМОНа, проведенное после командировки, показало значимое снижение уровня насыщенных (p = 0,040) и эссенциальных n-3 докозагексаеновой (p &lt; 0,001) и α-линоленовой кислот (p = 0,003) в липидах крови у 92 % и 68 % обследуемых соответственно. При этом доля докозагексаеновой кислоты в крови обратно коррелировала с показателем личностной тревожности (тест Спилбергера–Ханина) (r = -0,32; p = 0,028).ОБСУЖДЕНИЕ: Профессиональная деятельность сотрудников силовых ведомств и наличие регулярного психоэмоционального напряжения наиболее значимо оказывают влияние на эссенциальное звено жирных кислот. Проведенное исследование свидетельствует о необходимости оптимизации рациона питания сотрудников отдела специального назначения и дополнительного приема препаратов, в том числе обогащенных n-3 ПНЖК.</p></abstract><trans-abstract xml:lang="en"><p>INTRODUCTION: The study of the profile fatty acids (FA) as an energy and functional link of physical performance among enforcement agencies seems to be very relevant.OBJECTIVE: Assessment of the blood FA profile of the body of military before and after a 4-month special duty associated with health and life risks.MATERIALS AND METHODS: This prospective, between-subjects, repeated measures, study was conducted during 2014 year. 25 OMON fighters of the Komi Republic were examined before the trip and after a 4-month trip to the North Caucasus, where they constantly experienced combat stress. As a comparison group - employees of the Ministry of Emergency Situations (12 man). The level of FAs pool in total blood plasma lipids was determined by gas chromatography.RESULTS: During the initial examination of OMON fighters, a higher proportion of hypercholesterolemic myristic acid was revealed in both groups relative to the recommended norms. Its level was significantly higher in the special forces group and averaged 1.5 mol% (p = 0.028). The level of essential n-3 polyunsaturated fatty acids (PUFAs) in the blood plasma (α-linolenic and eicosapentaenoic acids) reduced relative to the baseline values in the participants against the background of a high proportion of linoleic acid was established, as evidenced by the high value of the n6/n3 index - 13.8 / 1 at the recommended standards of WHO 5- 7/1. A re-examination of OMON officers conducted after a trip showed a significant decrease in the level of saturated (p=0.040) and essential n-3 docosahexaenoic (p=0.000) and α-linolenic acids (p=0.003) in blood lipids in 92% and 68% of the subjects respectively. At the same time, the proportion of docosahexaenoic acid in the blood negative correlated with the indicator of personal anxiety (r= -0.32; p=0.028).DISCUSSION: The professional activity of military and the presence of regular psycho-emotional stress most significantly affect the essential part of fatty acids. The conducted study indicates the need to optimize the diet of participants and additional intake of food supplement, n-3 PUFAs enriched.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>морская медицина</kwd><kwd>жирные кислоты</kwd><kwd>n-3 докозагексаеновая кислота</kwd><kwd>α-линоленовая кислота</kwd><kwd>боевой стресс</kwd><kwd>бойцы ОМОНа</kwd><kwd>сотрудники МЧС</kwd><kwd>функциональное состояние</kwd></kwd-group><kwd-group xml:lang="en"><kwd>marine medicine</kwd><kwd>fatty acids</kwd><kwd>n-3 docosahexaenoic acid</kwd><kwd>α-linolenic acid</kwd><kwd>combat stress</kwd><kwd>OMON fighters</kwd><kwd>employees of the MES</kwd><kwd>functional state</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена за счет средств субсидии на выполнение Государственного задания № ГР1021051201877-3-3.1.8 (2022–2026).</funding-statement><funding-statement xml:lang="en">The study was carried out at the expense of subsidies for the implementation of State Assignment No. GR1021051201877-3-3.1.8 (2022–2026).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Солонин Ю.Г., Варламова Н.Г., Вахнина Н.А., Логинова Т.П., Людинина А.Ю., Марков А.Л., Потолицына Н.Н., Бойко Е.Р. 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